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Cardiac and pulmonary alterations in symptomatic and asymptomatic dogs infectednaturally with Leishmania (Leishmania) chagasi BJMBR
Alves,G.B.B.; Pinho,F.A.; Silva,S.M.M.S.; Cruz,M.S.P.; Costa,F.A.L..
Fifteen symptomatic and seven asymptomatic dogs infected naturally with Leishmania chagasi were examined in order to identify the presence of parasites and changes in heart and lung. Histopathological, cytological, and immunohistochemical analyses were performed on samples of heart and lung tissues. An inflammatory reaction characterized by inflammatory mononuclear, perivascular and intermuscular infiltrates was observed in both symptomatic and asymptomatic animals on histopathological analysis of the heart. In the lung, there was thickening of the alveolar septa due to congestion, edema, inflammatory infiltrate, and fibroblast proliferation. A focal reaction was observed although a diffuse reaction was present in both groups. On cytological examination,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Leishmaniasis; Dog; Lungs; Heart.
Ano: 2010 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000300014
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CD4+ T cells participate in the nephropathy of canine visceral leishmaniasis BJMBR
Costa,F.A.L.; Guerra,J.L.; Silva,S.M.M.S.; Klein,R.P.; Mendonça,I.L.; Goto,H..
Renal involvement in visceral leishmaniasis (VL) is very frequent. The renal lesions of humans and dogs are similar but their pathogenesis has not been clearly elucidated. There is growing evidence that the cellular immune response is involved in the pathogenesis of immunologically mediated glomerulonephritis. Since T cells could participate in the pathogenesis of nephropathy, in the present study we investigated the possible involvement of CD4+ and CD8+ T cells in the nephropathy of canine VL. Six dogs naturally infected with Leishmania (Leishmania) chagasi from the endemic area in the Northeast of Brazil, the town of Teresina in the State of Piauí, were studied. An expressive inflammatory infiltrate of CD4+ T cells both in glomeruli and in interstitium...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Visceral leishmaniasis; Dog; Leishmania (Leishmania) chagasi; Nephropathy; Immunoglobulin; T cells.
Ano: 2000 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000001200009
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Detection of immunoglobulin G in the lung and liver of hamsters with visceral leishmaniasis BJMBR
Mathias,R.; Costa,F.A.L.; Goto,H..
Several organs are affected in visceral leishmaniasis, not only those rich in mononuclear phagocytes. Hypergammaglobulinemia occurs during visceral leishmaniasis; anti-Leishmania antibodies are not primarily important for protection but might be involved in the pathogenesis of tissue lesions. The glomerulonephritis occurring in visceral leishmaniasis has been attributed to immune complex deposition but in other organs the mechanism has not been studied. In the current study we demonstrated the presence of IgG in the lung and liver of hamsters with visceral leishmaniasis. Hamsters were injected intraperitoneally with 2 x 10(7) amastigotes of Leishmania (Leishmania) chagasi and the presence of IgG in the liver and lung was evaluated at 7, 15, 30, 45, 80 and...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Leishmania (Leishmania) chagasi; Visceral leishmaniasis; Immunopathology; Immunoglobulin G; Liver; Lung.
Ano: 2001 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000400015
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Infecção por leptospira em bovinos e sua associação com transtornos reprodutivos e condições climáticas Arq. Bras. Med. Vet. Zootec.
Mineiro,A.L.B.B.; Bezerra,E.E.A.; Vasconcellos,S.A.; Costa,F.A.L.; Macedo,N.A..
Realizou-se estudo sorológico, por meio do teste de soroaglutinação microscópica, utilizando antígenos vivos, para pesquisa de aglutininas anti-leptospiras em bovinos de leite na Microrregião de Parnaíba, PI, em dois períodos do ano: estações seca e chuvosa. Das 1975 amostras analisadas, pertinentes a 16 rebanhos, 1044 (52,9%) mostraram-se positivas a pelo menos um sorovar e todos os rebanhos apresentaram animais reagentes. A prevalência variou entre 25% e 81%. O sorovar de maior prevalência foi Hardjo reagindo em 39,5%, seguido de Wolffi com 26,7% e Hebdomadis com 12,2%. Os sorovares mais freqüentes foram Hardjo e Wolffi presentes em 100% dos rebanhos. Foram ainda encontrados animais reagentes aos sorovares Australis, Bratislava, Autumnalis, Butembo,...
Tipo: Info:eu-repo/semantics/article Palavras-chave: Bovino; Transtornos reprodutivos; Leptospirose.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352007000500003
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Leishmania (Leishmania) chagasi-infected mice as a model for the study of glomerular lesions in visceral leishmaniasis BJMBR
Prianti,M.G.; Yokoo,M.; Saldanha,L.C.B.; Costa,F.A.L.; Goto,H..
Renal involvement in visceral leishmaniasis (VL) is very frequent but the pathogenesis of this nephropathy is poorly understood. In previous studies using dogs with VL we have detected new immunopathological elements in the glomeruli such as T cells and adhesion molecules. Although Leishmania (Leishmania) chagasi-infected dogs and hamsters are considered to be good models for VL, their use is limited for immunopathologic studies. The use of isogenic mouse strains susceptible to L. (L.) chagasi infection was an alternative but, on the other hand, the renal lesions of these animals have not yet been characterized. Thus, our purpose in the present study was to characterize mice infected with L. (L.) chagasi as a suitable model to study VL nephropathy. Kidney...
Tipo: Info:eu-repo/semantics/other Palavras-chave: Visceral leishmaniasis; Glomerulonephritis; Mice; Model; Leishmania (Leishmania) chagasi.
Ano: 2007 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000600011
Registros recuperados: 5
Primeira ... 1 ... Última
 

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